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Antigenic Specificity | AID (C-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises an epitope within the C-terminal region (CT) of Activation-induced cytidine deaminase (AID), a 24kDa homologue of the RNA-editing cytidine deaminase enzyme, APOBEC-1. . . Although the molecular mechanisms by which AID acts remain unclear, a growing number of studies reveal a requirement for AID during somatic hypermutation (SHM) and class switch recombination (CSR). These genetic modification events take place within highly specialised B cell germinal centres, during the final maturation stages of B cells, giving rise to high-affinity antibodies which use CSR to switch from IgM to IgG, IgA or IgE isotypes. MBS221871 recognises an epitope within the C-terminal region (CT) of Activation-induced cytidine deaminase (AID), |
Immunogen | Perservative Stabilisers: 0.02% Sodium Azide (NaN3). Preparation: Antisera to human AID (CT) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG pepared by affinity chromatography. |
Other Names | [single-stranded DNA cytosine deaminase; Single-stranded DNA cytosine deaminase; single-stranded DNA cytosine deaminase; cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; activation-induced cytidine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase], [AICDA; AICDA; AID; ARP2; CDA2; HIGM2; HEL-S-284; AID] |
Gene, Accession # | [AID], Gene ID: 57379, NCBI: NP_065712.1, UniProt: Q9GZX7 |
Catalog # | MBS223258 |
Price | $300 |
Order / More Info | AID (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |