AID (C-TERMINAL) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAID (C-TERMINAL)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.05 mg
ConcentrationIgG concentration 1.0mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThis item recognises an epitope within the C-terminal region (CT) of Activation-induced cytidine deaminase (AID), a 24kDa homologue of the RNA-editing cytidine deaminase enzyme, APOBEC-1. . . Although the molecular mechanisms by which AID acts remain unclear, a growing number of studies reveal a requirement for AID during somatic hypermutation (SHM) and class switch recombination (CSR). These genetic modification events take place within highly specialised B cell germinal centres, during the final maturation stages of B cells, giving rise to high-affinity antibodies which use CSR to switch from IgM to IgG, IgA or IgE isotypes. MBS221871 recognises an epitope within the C-terminal region (CT) of Activation-induced cytidine deaminase (AID),
ImmunogenPerservative Stabilisers: 0.02% Sodium Azide (NaN3). Preparation: Antisera to human AID (CT) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG pepared by affinity chromatography.
Other Names[single-stranded DNA cytosine deaminase; Single-stranded DNA cytosine deaminase; single-stranded DNA cytosine deaminase; cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; activation-induced cytidine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase], [AICDA; AICDA; AID; ARP2; CDA2; HIGM2; HEL-S-284; AID]
Gene, Accession #[AID], Gene ID: 57379, NCBI: NP_065712.1, UniProt: Q9GZX7
Catalog #MBS223258
Price$300
Order / More InfoAID (C-TERMINAL) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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