IL10 (Center), 27-53 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL10 (Center), 27-53
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: EBV, monkey)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionThis IL10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-53 amino acids from the Central region of human IL10. The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal t
Immunogenn/a
Other Names[Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF; IL10]
Gene, Accession #[IL10], Gene ID: 3586, NCBI: NP_000563.1, UniProt: P22301
Catalog #MBS9207395
Price$165, $370
Order / More InfoIL10 (Center), 27-53 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesTrajkov,D., et.al., Indian J Tuberc 56 (3), 117-131 (2009) Kim,J.M., et.al., J. Immunol. 148 (11), 3618-3623 (1992)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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