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Antigenic Specificity | NLK - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against NLK. It was validated on Western BlotTarget Description: NLK has a role in cell fate determination, required for differentiation of bone marrow stromal cells. NLK acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. NLK may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP By similarity.NLK is involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NLK |
Other Names | [serine/threonine-protein kinase NLK; Serine/threonine-protein kinase NLK; serine/threonine-protein kinase NLK; nemo like kinase; Nemo-like kinase; Protein LAK1] |
Gene, Accession # | [NLK], Gene ID: 51701, NCBI: NP_057315, UniProt: Q9UBE8 |
Catalog # | MBS3213043 |
Price | $335 |
Order / More Info | NLK - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |