Mouse TIE-2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Mouse TIE-2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.2 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Tie-1/Tie and Tie-2/Tek are receptor tyrosine kinases with unique structural characteristics including two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains, followed by three fibronectin type III-like repeats in the extracellular region, and a split tyrosine kinase domain in the cytoplasmic region. Tie-2 is involved in vascular stabilization and remodeling. Although less well understood, Tie-1 may also act as an ANG receptor, possibly in complex with Tie-2. Human Tie-2 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18 residue putative signal peptide, a 727 residue extracellular domain and a 354 residue cytoplasmic domain. Tie-2 is a receptor for the angiopoietin (ANG) family: ANG-1 |
| Immunogen | Immunogen: Recombinant mouse sTIE-2 (RT Cat# S01-M44). Preparation: Produced from sera of rabbits pre-immunized with highly pure (>95%) recombinant mouse soluble TIE-2 (Ala23-Ala737) produced in insect cells. |
| Other Names | [mouse TIE-2; Endothelial tyrosine kinase; Tyrosine kinase with Ig and EGF homology domains-2; CD202b], [Tek; Tek; Hyk; Tie2; tie-2; Cd202b; AA517024; Hyk; Tie-2; Tie2; mTIE2] |
| Gene, Accession # | [TIE-2], Gene ID: 21687, NCBI: NP_038718, UniProt: Q02858 |
| Catalog # | MBS691391 |
| Price | $390 |
| Order / More Info | Mouse TIE-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Partanen J and DJ Dumont (1999) Curr Top Microbiol Immunol 237:159. 2. Takakura N et al, (1998) Immunity 9:677. 3. Procopio W et al, (1999) J Biol Chem 274:30196. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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