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Antigenic Specificity | Phospho-TYK2 (Tyr433) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-TYK2 (Tyr433) Antibody detects endogenous levels of TYK2 only when phosphorylated at Tyr433. Description: Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.Subunit Structure: Interacts with JAKMIP1.Similarity: The FERM domain mediates interaction with JAKMIP1. Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human TYK2 around the phosphorylation site of Tyr433. Tissue Specificity: Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines. |
Other Names | [JTK 1; JTK1; Non receptor tyrosine protein kinase 2; Non receptor tyrosine protein kinase TYK2; Non-receptor tyrosine-protein kinase TYK2; OTTHUMP00000232745; OTTHUMP00000232746; OTTHUMP00000232748; Protein Tyrosine Kinase 2; TYK 2; Tyk2; TYK2_HUMAN; Tyrosine kinase 2] |
Gene, Accession # | [TYK2], Gene ID: 7297, NCBI: NP_003322.3, UniProt: P29597 |
Catalog # | MBS9610650 |
Price | $225, $280, $340 |
Order / More Info | Phospho-TYK2 (Tyr433) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |