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Antigenic Specificity | EGFR (Epidermal Growth Factor Receptor) |
Clone | [GFR450] |
Host Species | Mouse |
Reactive Species | humandoes not react with mouse. |
Isotype | IgG2a, kappa |
Format | CF488 conjugate |
Size | 0.5 mL |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas. |
Immunogen | Immunogen: Recombinant extracellular domain of human EGFR protein |
Other Names | [Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5] |
Gene, Accession # | [EGFR], Gene ID: 1956, NCBI: NP_005219.2, UniProt: P00533 |
Catalog # | MBS4380854 |
Price | $340 |
Order / More Info | EGFR (Epidermal Growth Factor Receptor) Antibody from MYBIOSOURCE INC. |
Product Specific References | Tungekar MF et. al. Journal of Clinical Pathology. 51: 583-587 (1998) |