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Antigenic Specificity | IRGM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of IRGM protein. IRGM encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of IRGM are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human IRGM protein at amino acid sequence of 101-150 |
Other Names | [Rabbit IRGM; Immunity-related GTPase family M protein; Immunity-related GTPase family M protein 1; Interferon-inducible protein 1; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; LRG-47] |
Gene, Accession # | [IRGM], Gene ID: 345611, NCBI: NP_001139277.1, UniProt: A1A4Y4 |
Catalog # | MBS9709532 |
Price | $130, $220, $325 |
Order / More Info | IRGM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |