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Antigenic Specificity | BNIP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human and mouse BNIP3. BNIP3 is a member of the apoptotic Bcl-2 protein family that is involved in both necrosis and apoptosis. Humans and other animals, as well as lower eukaryotes, encode several BNIP3 paralogues including human BNIP3L which induces apoptosis by interacting with viral and cellular anti-apoptosis proteins. BNIP3 interacts with the E1B 19kDa protein, which is responsible for the protection of virally induced cell death, as well as with E1B-like sequences of BCL2 which is also an apoptotic protector. The BNIP3 gene contains a BH3 domain and a transmembrane domain that have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by the BNIP3 gene is known to induce apopt |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids at the C-terminus of human BNIP3. |
Other Names | [BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2 interacting protein 3], [BNIP3; BNIP3; NIP3; NIP3] |
Gene, Accession # | [BNIP3], Gene ID: 664, NCBI: NP_004043.3, UniProt: Q12983 |
Catalog # | MBS191307 |
Price | $410 |
Order / More Info | BNIP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |