Edit |   |
---|---|
Antigenic Specificity | p53DINP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: A lower band at 18 kDa was detected in human spleen, and mouse liver and kidney tissue lysates, which may represent the p53DINP1-b form. Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible gene was identified recently and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein 1) and SIP (for stress induced protein) in human and mouse. A p53DINP1 antisense oligonucleotide inhibits and overexpression of p53DINP1 enhances Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks. p53DINP1 may regulate p53-dependent apoptosis through phosphoryl |
Immunogen | Immunogen Type: Peptide Immunogen Description: p53DINP1 antibody was raised with a synthetic peptide corresponding to 14 amino acids near the amino terminus of human p53DINP1. |
Other Names | [p53DINP1, SIP] |
Gene, Accession # | [p53DINP1], Gene ID: 94241, NCBI: NP_001129205.1, UniProt: Q96A56 |
Catalog # | MBS9402840 |
Price | $320 |
Order / More Info | p53DINP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |