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Antigenic Specificity | TNFRSF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TNFRSF4 protein. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human tumor necrosis factor receptor superfamily, member 4 |
Other Names | [OX40; ACT35; CD134; IMD16; TXGP1L] |
Gene, Accession # | [TNFRSF4], Gene ID: 7293, NCBI: NP_003318.1, UniProt: P43489 |
Catalog # | MBS9408223 |
Price | $255 |
Order / More Info | TNFRSF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |