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Antigenic Specificity | SMAD4 (C-term), 400-428 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, porcine, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SMAD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-428 amino acids from the C-terminal region of human SMAD4. SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor. |
Immunogen | n/a |
Other Names | [Mothers against decapentaplegic homolog 4; MAD homolog 4; Mothers against DPP homolog 4; Deletion target in pancreatic carcinoma 4; SMAD family member 4; SMAD 4; Smad4; hSMAD4; SMAD4; DPC4; MADH4] |
Gene, Accession # | [SMAD4], Gene ID: 4089, NCBI: NP_005350.1, UniProt: Q13485 |
Catalog # | MBS9213375 |
Price | $165, $370 |
Order / More Info | SMAD4 (C-term), 400-428 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sekiya, T., et al., Biochem. Biophys. Res. Commun. 320(3):680-684 (2004). Horvath, L.G., et al., Prostate 59(3):234-242 (2004). Li, L., et al., Mol. Cell. Biol. 24(2):856-864 (2004). Wan, M., et al., J. Biol. Chem. 279(15):14484-14487 (2004). Maru, D., et al., Oncogene 23(3):859-864 (2004). |