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Antigenic Specificity | ETAA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ETAA1 antibody detects endogenous levels of total ETAA1. Function: Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717).Subunit Structure: Interacts (via RBM1 motif) with RPA1 (PubMed:27601467, PubMed:27723720, PubMed:27723717). Interacts (via RBM2 motif) with RPA2 (PubMed:27601467, PubMed:27723720, PubMed:27723717). Interacts (via the ATR |
Immunogen | Immunogen: A synthesized peptide derived from human ETAA1 Subcellular Location: Cytoplasm. Tissue Specificity: Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines. |
Other Names | [Etaa1; ETAA1_HUMAN; ETAA16; Ewing''s tumor-associated antigen 1; Ewing''s tumor-associated antigen 16] |
Gene, Accession # | [ETAA1], Gene ID: 54465, NCBI: NP_061875.2, UniProt: Q9NY74 |
Catalog # | MBS9609829 |
Price | $240, $280 |
Order / More Info | ETAA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |