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Antigenic Specificity | Human CD66a (CEACAM1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg, 0.2 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD66a is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. However, CD66a combines structural features of the immunoglobulin superfamily with functional properties of cadherins.The mechanism (s) by which CD66a transmits signals.are unclear. However, CD66a is phosphorylated on its cytoplasmic domain, largely on tyrosine with a lower level of phosphoserine, in neutrophils and colon cancer cells. While at least eight isoforms of CD66a derived from differential splicing have been described, only those isoforms with a long cytoplasmic tail can be phosphorylated on tyrosine. In addition, associated protein tyrosine kinase and phosphatase activities may be involved in CD66a signaling. |
Immunogen | Source Note: Polyclonal CD66a antibody was produced from sera of rabbits immunized with C terminal antigenic determinants of CD66a. |
Other Names | [Rabbit Human CD66a (CEACAM1) purified; cd66a; cd-66a; cd-66; cd66; CEACAM1;; PAb], [CEACAM1; BGP; BGP1; BGP-1] |
Gene, Accession # | [CD66], Gene ID: 634, NCBI: NP_001020083.1, UniProt: P13688 |
Catalog # | MBS551051 |
Price | $375, $495 |
Order / More Info | Human CD66a (CEACAM1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |