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Antigenic Specificity | Beclin 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Beclin 2 antibody is human specific. At least two isoforms of Beclin 2 are known to exist; this antibody will only detect the longer isoform. Beclin 2 antibody is predicted to not cross-react with Beclin 1. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells (1,2). Beclin 2 is a mammalian specific homolog of the autophagy protein Beclin 1 (3). Like Beclin 1, Beclin 2 interacts with Bcl-2 and class III PI3K complex components. However, Beclin 2 functions in an additional lysosomal degradation pathway and is required for ligand-induced endolysosomal degradation of several G protein-coupled receptors ( |
Immunogen | Immunogen: Beclin 2 antibody was raised against a 16 amino acid peptide near the amino terminus of human Beclin 2. Buffer: Beclin 2 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [BECN2; BECN1L1; Beclin-1-like protein 1; Beclin 1 autophagy related pseudogene 1; BECN1P1; beclin 1, autophagy related, pseudogene 1], [BECN1P1; BECN1P1; BECN2; BECN1L1] |
Gene, Accession # | [BECN1P1], Gene ID: 441925, NCBI: NP_001277622, UniProt: A8MW95 |
Catalog # | MBS153642 |
Price | $375 |
Order / More Info | Beclin 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |