Beclin 2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBeclin 2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSpecificity: Beclin 2 antibody is human specific. At least two isoforms of Beclin 2 are known to exist; this antibody will only detect the longer isoform. Beclin 2 antibody is predicted to not cross-react with Beclin 1. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells (1,2). Beclin 2 is a mammalian specific homolog of the autophagy protein Beclin 1 (3). Like Beclin 1, Beclin 2 interacts with Bcl-2 and class III PI3K complex components. However, Beclin 2 functions in an additional lysosomal degradation pathway and is required for ligand-induced endolysosomal degradation of several G protein-coupled receptors (
ImmunogenImmunogen: Beclin 2 antibody was raised against a 16 amino acid peptide near the amino terminus of human Beclin 2. Buffer: Beclin 2 antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[BECN2; BECN1L1; Beclin-1-like protein 1; Beclin 1 autophagy related pseudogene 1; BECN1P1; beclin 1, autophagy related, pseudogene 1], [BECN1P1; BECN1P1; BECN2; BECN1L1]
Gene, Accession #[BECN1P1], Gene ID: 441925, NCBI: NP_001277622, UniProt: A8MW95
Catalog #MBS153642
Price$375
Order / More InfoBeclin 2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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