NFAM1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-NFAM1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | NFAM1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NFAM1 antibody detects endogenous levels of total NFAM1. Function: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.Subunit Structure: No direct interaction with the B-cell antigen receptor (BCR). Interacts with SYK; probably involved in BCR signaling. Interacts with ZAP70 (By similarity).Post-translational Modifications: N-glycosylated.Similarity: The ITAM domain displays no close similarity to a |
| Immunogen | Immunogen: A synthesized peptide derived from human NFAM1 Subcellular Location: Type I Membrane Protein. Tissue Specificity: Highly expressed in neutrophils, primary monocytes, mast cells, monocytic cell lines and lymphocytes. Also expressed in spleen B and T-cells, and lung. Expressed at low level in non-immune tissue. |
| Other Names | [Calcinerin/NFAT activating ITAM containing protein; CNAIP; NFAT activation molecule 1 precursor] |
| Gene, Accession # | [NFAM1], Gene ID: 150372, NCBI: NP_001305252.1, UniProt: Q8NET5 |
| Catalog # | MBS9609343 |
| Price | $240, $280 |
| Order / More Info | NFAM1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies