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Antigenic Specificity | HLA-DQB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.5 mg/mL |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total HLA-DQB1 protein. HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and |
Immunogen | Immunogen: Fusion protein of human HLA-DQB1 Immunogen Type: Peptide |
Other Names | [IDDM1; CELIAC1; HLA-DQB] |
Gene, Accession # | [HLA-DQB1], Gene ID: 3119, NCBI: NP_001230891.1, UniProt: P01920 |
Catalog # | MBS9430271 |
Price | $255 |
Order / More Info | HLA-DQB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |