HLA-DQB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHLA-DQB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.5 mg/mL
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total HLA-DQB1 protein. HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and
ImmunogenImmunogen: Fusion protein of human HLA-DQB1 Immunogen Type: Peptide
Other Names[IDDM1; CELIAC1; HLA-DQB]
Gene, Accession #[HLA-DQB1], Gene ID: 3119, NCBI: NP_001230891.1, UniProt: P01920
Catalog #MBS9430271
Price$255
Order / More InfoHLA-DQB1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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