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Antigenic Specificity | FceRI, alpha (Fc epsilon RI, IgE Receptor) |
Clone | [4i39] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | ascites |
Size | 0.2 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human FceRI alpha (45kD); nonspeci c bands at 28kD, and 60kD were observed in Immunoprecipitation/Western Blot of untransfected CHO cells. The allergic reaction is mediated through the IgE high affinity receptor (FceRI). When a multivalent antigen is presented, a redistribution of the monomeric IgE-FceRI receptor complexes cause the degranulation of mast cells and basophils, resulting in the subsequent release of factors responsible for the allergic reaction. The FceRI receptor is a tetrameric complex, consisting of a a-chain, b-chain and a dimeric g-chain. While the a-chain is primarily involved with the binding of IgE, the signal is transferred through the g subunit, which contains the immunoreceptor tyrosine activation motifs |
Immunogen | Immunogen: Transfected cells expressing the alpha chain of the human high-af?nity receptor for immunoglobulin E (FceRI). |
Other Names | [-FceRI, alpha (Fc epsilon RI, IgE Receptor)], [FCER1A; FCER1A; FCE1A; FcERI; FCE1A; FcERI] |
Gene, Accession # | Gene ID: 2205, NCBI: AAH15195.1, UniProt: P12319 |
Catalog # | MBS631886 |
Price | $610 |
Order / More Info | FceRI, alpha (Fc epsilon RI, IgE Receptor) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |