FceRI, alpha (Fc epsilon RI, IgE Receptor) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFceRI, alpha (Fc epsilon RI, IgE Receptor)
Clone[4i39]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG
Formatascites
Size0.2 mL
Concentrationn/a
ApplicationsELISA (EL/EIA), Immunoprecipitation (IP)
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DescriptionRecognizes human FceRI alpha (45kD); nonspeci c bands at 28kD, and 60kD were observed in Immunoprecipitation/Western Blot of untransfected CHO cells. The allergic reaction is mediated through the IgE high affinity receptor (FceRI). When a multivalent antigen is presented, a redistribution of the monomeric IgE-FceRI receptor complexes cause the degranulation of mast cells and basophils, resulting in the subsequent release of factors responsible for the allergic reaction. The FceRI receptor is a tetrameric complex, consisting of a a-chain, b-chain and a dimeric g-chain. While the a-chain is primarily involved with the binding of IgE, the signal is transferred through the g subunit, which contains the immunoreceptor tyrosine activation motifs
ImmunogenImmunogen: Transfected cells expressing the alpha chain of the human high-af?nity receptor for immunoglobulin E (FceRI).
Other Names[-FceRI, alpha (Fc epsilon RI, IgE Receptor)], [FCER1A; FCER1A; FCE1A; FcERI; FCE1A; FcERI]
Gene, Accession #Gene ID: 2205, NCBI: AAH15195.1, UniProt: P12319
Catalog #MBS631886
Price$610
Order / More InfoFceRI, alpha (Fc epsilon RI, IgE Receptor) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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