Phospho-NFAT5/TonEBP (Ser145) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-NFAT5/TonEBP (Ser145) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-NFAT5/TonEBP (Ser145) Antibody detects endogenous levels of NFAT5/TonEBP only when phosphorylated at Ser145. Description: Transcription factor involved, among others, in the transcriptional regulation of osmoprotective and inflammatory genes. Mediates the transcriptional response to hypertonicity (PubMed:10051678). Positively regulates the transcription of LCN2 and S100A4 genes; optimal transactivation of these genes requires the presence of DDX5/DDX17 (PubMed:22266867). Binds the DNA consensus sequence 5'-[ACT][AG]TGGAAA[CAT]A[TA][ATC][CA][ATG][GT][GAC][CG][CT]-3' (PubMed:10377394).Post Translational Modifications: Phosphorylated (PubMed:10377394). Phosphorylated at Thr-135 by CDK5 in response to osmotic stress |
| Immunogen | Immunogen: A synthesized peptide derived from human NFAT5/TonEBP around the phosphorylation site of Ser145. Tissue Specificity: Widely expressed, with highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. |
| Other Names | [Glutamine rich protein H65; KIAA0827; NF AT5; NF-AT5; NFAT 5; NFAT L1; NFAT like protein 1; NFAT5; NFAT5_HUMAN; NFATL 1; NFATL1; NFATZ; Nuclear factor of activated T cells 5; Nuclear factor of activated T cells 5 tonicity responsive; Nuclear factor of activated T cells; Nuclear factor of activated T-cells 5; OREBP; Osmotic response element binding protein; T cell transcription factor NFAT 5; T cell transcription factor NFAT5; T-cell transcription factor NFAT5; TonE binding protein; TonE-binding protein; TonEBP; Tonicity responsive enhancer binding protein; Tonicity-responsive enhancer-binding protein] |
| Gene, Accession # | [NFAT5/TonEBP], Gene ID: 10725, NCBI: NP_001106649.1, UniProt: O94916 |
| Catalog # | MBS9610524 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-NFAT5/TonEBP (Ser145) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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