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Antigenic Specificity | TLR4 (Center), 669-698 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, hamster, porcine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TLR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 669-698 amino acids from the Central region of human TLR4. TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopu |
Immunogen | n/a |
Other Names | [Toll-like receptor 4; hToll; CD284; TLR4] |
Gene, Accession # | [TLR4], Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206 |
Catalog # | MBS9206134 |
Price | $165, $370 |
Order / More Info | TLR4 (Center), 669-698 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sam-Agudu, N.A., et al. Am. J. Trop. Med. Hyg. 82(4):548-555(2010) # Palomino-Morales, R.J., et al. Arthritis Res. Ther. 12 (2), R51 (2010) # Rigoli, L., et al. Anticancer Res. 30(2):513-517(2010) # da Silva Correia, J., et al. J. Biol. Chem. 277(3):1845-1854(2002) # Shimazu, R., et al. J. Exp. Med. 189(11):1777-1782(1999) |