Phospho-Ser778 Dynamin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Ser778 Dynamin |
| Clone | polyclonal |
| Host Species | Sheep |
| Reactive Species | rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Specific for the ~95k dynamin protein phosphorylated at Ser778. Labels the purified protein phosphorylated in vitro by cdk5 but not by PKC. Does not cross react with other purified substrates of cdk5 (e.g. amphiphysin and synapsin). Immunolabeling is blocked by ?-phosphatase treatment. Affinity purified sheep polyclonal antibody |
| Immunogen | Antigen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser778 of rat dynamin. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser778 conjugated to KLH. Immunogen Species: Rat |
| Other Names | [dynamin-1; Dynamin-1; dynamin-1; D100; B-dynamin; dynamin, brain; dynamin 1; B-dynamin; D100; Dynamin, brain], [Dnm1; Dnm1; Dnm; Dnm] |
| Gene, Accession # | [DNM1], Gene ID: 140694, NCBI: NP_542420.1, UniProt: P21575 |
| Catalog # | MBS502029 |
| Price | $360 |
| Order / More Info | Phospho-Ser778 Dynamin Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Cousin MA, Tan TC, Robinson PJ (2001) Protein phosphorylation is required for endocytosis in nerve terminals: potential role for the dephosphins dynamin I and synaptojanin, but not AP180 or amphiphysin. J Neurochem 76:105-116.• Graham ME, O'Callaghan DW, McMahon HT, Burgoyne RD (2002) Dynamin-dependent and dynamin-independent processes contribute to the regulation of single vesicle release kinetics and quantal size. Proc Natl Acad Sci USA 99:7124-7129.• Tan TC, Valova VA, Malladi CS, Graham ME, Berven LA, Jupp OJ, Hansra G, McClure SJ, Sarcevic B, Boadle RA, Larsen MR, Cousin MA, Robinson PJ (2003) cdk5 is essential for synaptic vesicle endocytosis. Nat Cell Biol 5:701-710.• Tsuboi T, Terakawa S, Scalettar BA, Fantus C, Roder J, Jeromin A (2002) Sweeping model of dynamin activity - Visualization of coupling between exocytosis and endocytosis under an evanescent wave microscope with green fluorescent proteins. J Biol Chem 277:15957-15961.• Clayton EL, Sue N, Smillie KJ, O'Leary T, Bache N, Cheung G, Cole AR, Wyllie DJ, Sutherland C, Robinson PJ, Cousin MA. (2010) Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles. Nat Neurosci. 13(7):845-51. |
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MYBIOSOURCE INC.
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