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Antigenic Specificity | GSK-3beta |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | peroxidase (HRP) conjugate |
Size | 0.1 mL |
Concentration | 100ug/200ul |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human GSK-3beta. Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3beta and GSK-3beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility. |
Immunogen | n/a |
Other Names | [glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta] |
Gene, Accession # | [GSK-3beta], Gene ID: 790875, NCBI: NP_001094780.1 |
Catalog # | MBS4152633 |
Price | $445 |
Order / More Info | GSK-3beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |