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Antigenic Specificity | Claudin-19 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein. The product of CLDN19 belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in CLDN19 are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Claudin-19 at AA range: 50-130 |
Other Names | [Rabbit Claudin-19; Claudin-19] |
Gene, Accession # | [CLDN19], Gene ID: 149461, NCBI: NP_001116867.1, UniProt: Q8N6F1 |
Catalog # | MBS9701708 |
Price | $130, $220, $325 |
Order / More Info | Claudin-19 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |