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Antigenic Specificity | GRB10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least three isoforms of GRB10 are known to exist; this antibody will detect all three isoforms. GRB10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules and function in diverse cellular processes. GRB10 is a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of GRB10 inhibits tyrosine kinase activity and results in growth suppression. GRB10 can also interact with the L isoform of the proapoptotic protein Bim. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the bra |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 17 amino acid peptide near the carboxy terminus of human GRB10. |
Other Names | [Growth factor receptor-bound 10, RSS, IRBP, MEG1, GRB-IR] |
Gene, Accession # | [GRB10], Gene ID: 2887, NCBI: NP_005302 |
Catalog # | MBS9408894 |
Price | $320 |
Order / More Info | GRB10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |