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Antigenic Specificity | SCN4A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SCN4A protein. This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.George A.L. Jr., Ann. Neurol. 31:131-137(1992).Wang J., Biochem. Biophys. Res. Commun. 182:794-801(1992).Tsujino A., Proc. Natl. Acad. Sci. U.S.A. 100:7377-7382(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human SCN4A. |
Other Names | [Sodium channel protein type 4 subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4; Sodium channel protein skeletal muscle subunit alpha; SkM1] |
Gene, Accession # | [SCN4A], Gene ID: 6329, NCBI: NP_000325.4, UniProt: P35499 |
Catalog # | MBS9401263 |
Price | $200, $255 |
Order / More Info | SCN4A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |