IgG4, Human Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-IgG4, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | IgG4, Human |
| Clone | polyclonal |
| Host Species | Sheep |
| Reactive Species | human |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 0.5 mL |
| Concentration | 0.5 mg/ml |
| Applications | Immunoelectrophoresis (IEP), Western Blot (WB), Fluoroimmunoassay (FIA), Immunohistochemistry (IHC), Fluorescent Microscopy |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IgG4 is a T-helper cell 2-dependent immunoglobulin subtype with many physiologic and morphologic peculiarities. IgG4-associated autoimmune diseases are systemic diseases affecting multiple organs of the body. Any organ system can be affected, including the biliary pathways, salivary glands, kidneys, lymph nodes, thyroid gland, blood vessels and skin. This chronic inflammatory condition is characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells resulting in diffuse organ swelling, tissue-destructive lesions and fibrosis. This can lead to organ dysfunction or even organ failure, if not treated. Pemphigus is a chronic blistering skin disease caused by IgG4-autoantibodies which can be detected in the patient's skin |
| Immunogen | Immunogen: Purified human IgG4 |
| Other Names | n/a |
| Gene, Accession # | [IgG4] |
| Catalog # | MBS397249 |
| Price | $1085 |
| Order / More Info | IgG4, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kleger A, Seufferlein T, Wagner M, Tannapfel A, Hoffmann TK, Mayerle J (2015) IgG4-associated autoimmune diseases - polymorphous presentation complicates diagnosis and treatment. Dtsch Arztebl Int; 112: 128-35. 2. Stone et al. (2012). Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations. Arthritis & Rheumatism. 64 (10): 3061-3067. 3. Deshpande et al. (2012). Consensus statement on the pathology of IgG4-related disease. Modern Pathology. 25 (9): 1181-1192. 4. A. Fernandez-Flores (2012) The role of IgG4 in cutaneous pathology. Rom J Morphol Embryol, 53(2):221-231. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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