ABCA4 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ABCA4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ABCA4 antibody detects endogenous levels of total ABCA4. Function: In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.Similarity: Belongs to the ABC transporter sup |
| Immunogen | Immunogen: A synthesized peptide derived from human ABCA4 Subcellular Location: Membrane. Localized to outer segment disk edges of rods and cones, with around one million copies/photoreceptor. Tissue Specificity: Retinal-specific. Seems to be exclusively found in the rims of rod photoreceptor cells. |
| Other Names | [ABC 10; ABC A4; ABC transporter, retinal-specific; ABC10; ABCA 4; abcA4; ABCA4_HUMAN; ABCR; ARMD 2; ARMD2; ATP binding cassette 10; ATP binding cassette sub family A member 4; ATP binding cassette sub family A member4; ATP binding cassette transporter; ATP binding cassette transporter retinal specific; ATP binding cassette, sub family A (ABC1), member 4; ATP binding cassette, sub family A (ABC1), member4; ATP binding cassette10; ATP binding transporter, retina specific; ATP-binding cassette sub-family A member 4; CORD 3; CORD3; DKFZp781N1972; FFM; FLJ17534; Photoreceptor rim protein; Retina specific ABC transporter; Retinal specific ATP binding cassette transporter; Retinal-specific ATP-binding cassette transporter; RIM ABC transporter; RIM protein; RmP; RP 19; RP19; Stargardt disease protein; STGD; STGD1] |
| Gene, Accession # | [ABCA4], Gene ID: 24, NCBI: NP_000341.2, UniProt: P78363 |
| Catalog # | MBS9610168 |
| Price | $240, $280 |
| Order / More Info | ABCA4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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