ABCB11 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ABCB11 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Bile salt export pump(ABCB11) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: ABCG5 (Atp-binding cassette, subfamily g, member 5) also known as STEROLIN 1, is a protein that in humans is encoded by the ABCG5 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. The ABCG5 gene contains 13 exons and spans about 28 kb. The ABCG5 gene is mapped on 2p21. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This g |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ABCB11 (1175-1199aa KYGDNTKEIPMERVIAAAKQAQLHD), different from the related mouse and rat sequences by three amino acids. Ig Type: Rabbit IgG |
| Other Names | [Bile salt export pump; ABC member 16, MDR/TAP subfamily; ABCB1; Abcb11; ABCBB_HUMAN; ATP binding cassette sub family B (MDR/TAP) member 11; ATP binding cassette sub family B member 11; ATP-binding cassette sub-family B member 11; Bile salt export pump; BRIC2; Bsep; PGY4; progressive familial intrahepatic cholestasis 2; Sister of P glycoprotein; Spgp; ATP-binding cassette, sub-family B (MDR/TAP), member 11], [ABCB11; ABCB11; BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2; BSEP] |
| Gene, Accession # | [ABCB11], Gene ID: 8647, NCBI: NP_003733.2, UniProt: O95342 |
| Catalog # | MBS177975 |
| Price | $315 |
| Order / More Info | ABCB11 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Knisely AS, Strautnieks SS, Meier Y, Stieger B, Byrne JA, Portmann BC, Bull LN, Pawlikowska L, Bilezikci B, Ozcay F, Laszlo A, Tiszlavicz L, Moore L, Raftos J, Arnell H, Fischler B, Nemeth A, Papadogiannakis N, Cielecka-Kuszyk J, Jankowska I, Paw?owska J, Melin-Aldana H, Emerick KM, Whitington PF, Mieli-Vergani G, Thompson RJ (August 2006). Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency. Hepatology 44 (2): 478-86. 2. Noe J, Kullak-Ublick GA, Jochum W, Stieger B, Kerb R, Haberl M, Mullhaupt B, Meier PJ, Pauli-Magnus C (September 2005). Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis. J. Hepatol. 43 (3): 536-43. 3. Strautnieks SS, Bull LN, Knisely AS, Kocoshis SA, Dahl N, Arnell H, Sokal E, Dahan K, Childs S, Ling V, Tanner MS, Kagalwalla AF, Nemeth A, Pawlowska J, Baker A, Mieli-Vergani G, Freimer NB, Gardiner RM, Thompson RJ (November 1998). A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis. Nat. Genet. 20 (3): 233-8. 4. Strautnieks, S., Kagalwalla, A. F., Tanner, M. S., Knisely, A. S., Bull, L. N., Freimer, N. B., Kocoshis, S. A., Gardiner, R. M., Thompson, R. J.Identification of a second locus for progressive familial intrahepatic cholestasis on chromosome 2q24.Medizinische Genetik9: 16-only, 1997. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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