Human p70S6K (C-TERMINAL) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human p70S6K (C-TERMINAL) |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | mouse (expected from sequence), rabbit (expected from sequence), rat (expected from sequence) |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 0.5mg/ml |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item specifically recognises an epitope within the C-terminal (CT) region of human p70S6K, otherwise known as RPS6KB1 (Ribosomal protein S6 kinase beta-1), a serine/threonine kinase which acts upon 40S ribosomal protein S6 to induce protein synthesis, allowing for efficient G1 phase progression.. . p70S6K is activated following phosphorylation of several sites, in response to hormones, growth factors, mitogenic stimuli and physical exercise, and is a downstream effector in the AKT/mTOR (mammalian target of rapamycin) signalling pathway. Studies have implicated that as well as its role in translation, p70S6K acts as a regulator of cell motility, invasion, and cytoskeletal reorganization. MBS223128 specifically recognises an epitope wi |
| Immunogen | Immunogen: Peptide sequence C-MISKRPEHLRMNL corresponding to the C-Terminal region of p70S6K (NP 003152.1). Buffer Solution: TRIS buffered saline Antiserum Preparation: Antiserum to human p70S6K (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
| Other Names | [ribosomal protein S6 kinase beta-1 isoform b; Ribosomal protein S6 kinase beta-1; ribosomal protein S6 kinase beta-1; p70 S6 kinase, alpha; ribosomal protein S6 kinase I; serine/threonine kinase 14 alpha; serine/threonine-protein kinase 14A; ribosomal protein S6 kinase, 70kDa, polypeptide 1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA], [RPS6KB1; RPS6KB1; S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha; STK14A; S6K-beta-1; S6K1; P70S6K1; p70-S6K 1; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA] |
| Gene, Accession # | [p70S6K], Gene ID: 6198, NCBI: NP_001258971.1, UniProt: P23443 |
| Catalog # | MBS223128 |
| Price | $550 |
| Order / More Info | Human p70S6K (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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