Edit |   |
---|---|
Antigenic Specificity | PDCL3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PDCL3 antibody is human, mouse and rat reactive. PDCL3 antibody is predicted to not cross-react with other members of the PDCL protein family. Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling (1,2). PDCL3 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain (3). Along with the related protein PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding (4). Modulation of PDCL3 levels by MAPK phosphorylation and RhoA-dependent changes also promote cytoskeletal remodeling (5). |
Immunogen | Immunogen: PDCL3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PDCL3. Buffer: PDCL3 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PDCL3; VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A; PhLP2A; Phosducin-like protein 3; VIAF-1; phosducin-like 3], [PDCL3; PDCL3; VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A; PhLP2A; VIAF1; VIAF-1] |
Gene, Accession # | [PDCL3], Gene ID: 79031, NCBI: NP_076970, UniProt: Q9H2J4 |
Catalog # | MBS153675 |
Price | $375 |
Order / More Info | PDCL3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |