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Antigenic Specificity | Human PDGFR-beta |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: PDGF is a major serum mitogen that can exist as a homo or heterodimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA, PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF Ralpha binds all three PDGF isoforms with high affinity, PDGF Rbeta binds PDGF-BB only with highaffinity. Both PDGF Ralpha and PDGF Rbeta are members of the class III subfamily of receptor tyrosine kinases (RTK) that also includes the receptors for M CSF, SCF and Flt3 ligand. All class III RTKs are characterized by the presence of five immunoglobulin-like domains in their extracellular region and a split kinase domain in their intracellular regi |
Immunogen | Immunogen: Recombinant human PDGFR beta extracellular domain |
Other Names | [PDGFRB; JTK12; PDGFR; CD140B; PDGFR1; PDGFR-1], [PDGFRB; PDGFRB; IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1; PDGFR; PDGFR1; PDGF-R-beta; PDGFR-beta; PDGFR-1] |
Gene, Accession # | [PDGFR-beta], Gene ID: 5159, NCBI: NP_002600.1, UniProt: P09619 |
Catalog # | MBS692535 |
Price | $490 |
Order / More Info | Human PDGFR-beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |