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Antigenic Specificity | DEDAF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cell death signal are transduced by death domain, death effector domain, and caspase recruitment domain containing molecules. A novel protein that interacts with DED of caspase-8 and -10, and FADD was recently identified and designated DEDAF. DEDAF is identical to the transcriptional repressor RYBP. DEDAF interacts with FADD and augments the formation of CD95/FADD/caspase-8 complexes at the cytoplasm. DEDAF also interacts with DED-containing DNA biding protein in the nucleus, indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis. |
Immunogen | Immunogen: DEDAF antibody was raised in Rabbit using synthetic peptide surrounding amino acid 218 of human DEDAF as the immunogen. |
Other Names | [Rabbit DEDAF; DEDAF; DEDAF; RYBP; AAP1; DED-associated factor; APAP-1; YEAF1; YY1 and E4TF1-associated factor 1; Apoptin-associating protein 1; RING1 and YY1-binding protein; APAP-1; Death effector domain-associated factor] |
Gene, Accession # | [DEDAF] |
Catalog # | MBS5311258 |
Price | $475 |
Order / More Info | DEDAF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |