IL-18 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL-18
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein G purified
Size0.1 mg, 0.2 mg
Concentrationn/a
ApplicationsWestern Blot (WB), IHC (Immunohistochemistry), ELISA (EIA)
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DescriptionIL18 is synthesized as a biologically inactive precursor protein that has limited biological activity. The proform of IL18 is processed by one of the caspases, Caspase-1, to generate the 18 kDa bioactive molecule. IL-18 is produced during the acute immune response by macrophages and immature dendritic cells. Interleukin-18 is expressed by a variety of immune and non-immune cells, including monocytes and macrophages. IL18 is one of the pro- inflammatory cytokines. The activities of IL18 appear to be species specific. An important function of IL18 is the regulation of functionally distinct subsets of T-helper cells required for cell mediated immune responses (Nakanishi et al, 2001). IL18 functions as a growth and differentiation factor for Th
ImmunogenSource Note: Polyclonal Interleukin-18 antibody was produced from sera of rabbits immunized with synthetic protein containing Interleukin-18 N-terminus antigenic determinants.
Other Names[Rabbit IL-18 purified; IGIF; IL1F4; IL18; il-18;; pab], [IL18; IGIF; IL1F4; IL-18; IFN-gamma-inducing factor; IL-1 gamma]
Gene, Accession #[IL-18], Gene ID: 3606, NCBI: NP_001230140.1, UniProt: Q14116
Catalog #MBS551052
Price$280, $385
Order / More InfoIL-18 Antibody from MYBIOSOURCE INC.
Product Specific References• IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction.PNAS, Sep 2009; 10.1073/pnas.0908924106. • IL-18 and urinary ngal predict dialysis and graft recovery after kidney transplantation.J. Am. Soc. Nephrol., Sep 2009; 10.1681/ASN.2009030264. • a functional polymorphism in IL-18 is associated with severity of bronchial asthma.Am. J. Respir. Crit. Care Med., Sep 2009; 10.1164/rccm.200905-0652 degree C. • il-12p40 and IL-18 play pivotal roles in orchestrating the cell-mediated immune response to a poxvirus infection.J. Immunol., Sep 2009; 183: 3324 - 3331. • neutrophil chemokines and their role in IL-18-mediated increase in neutrophil o2- production and intestinal edema following alcohol intoxication and burn injury.Am J Physiol Gastrointest Liver Physiol, Aug 2009; 297: G340 - G347.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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