FAP1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | FAP1 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences, on substrate such as alpha-2-antiplasmin SERPINF2 and SPRY2 (PubMed: 14751930, PubMed: 16223769, PubMed: 16480718, PubMed: 16410248, PubMed: 17381073, PubMed: 18095711, PubMed: 21288888, PubMed: 24371721). Degrade also gelatin, heat-denatured type I collagen, but not native collagen type I and IV, vibronectin, tenascin, laminin, fibronectin, fibrin or case |
| Immunogen | Immunogen: A synthesized peptide derived from human FAP1. Subcellular Localization: Prolyl endopeptidase FAP: Cell surface. Cell membrane; Single- pass type II membrane protein. Cell projection, lamellipodium membrane; Single-pass type II membrane protein. Cell projection, invadopodium membrane; Single-pass type II membrane protein. Cell projection, ruffle membrane; Single-pass type II membrane protein. Membrane; Single-pass type II membrane protein. Localized on cell surface with lamellipodia a |
| Other Names | [Prolyl endopeptidase FAP; 3.4.21.26; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; 3.4.14.5; Fibroblast activation protein alpha; FAPalpha; Gelatine degradation protease FAP; 3.4.21.-; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; SIMP; Surface-expressed protease; Seprase; Antiplasmin-cleaving enzyme FAP; soluble form; APCE; 3.4.14.5; 3.4.21.-; 3.4.21.26; FAP], [FAP] |
| Gene, Accession # | [FAP1], Gene ID: 2191, NCBI: NP_001278736.1, UniProt: Q12884 |
| Catalog # | MBS179319 |
| Price | $160, $340, $340 |
| Order / More Info | FAP1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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