Human CD81 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD81 antibody, protein, ELISA kits.
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| Antigenic Specificity | Human CD81 |
| Clone | [QV-6A8-S3] |
| Host Species | Rat |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), CELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: anti-human CD81 (TAPA-1). Background: CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL) (1). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins (2,3). CD81 is an essential HCV host factor as silencing of CD81 expression by CD81- |
| Immunogen | Immunogen: Immunogen: cDNA |
| Other Names | [TAPA-1], [CD81; CD81; S5.7; CVID6; TAPA1; TSPAN28; TAPA1; TSPAN28; Tspan-28] |
| Gene, Accession # | Gene ID: 975, NCBI: NP_004347.1, UniProt: P60033 |
| Catalog # | MBS468029 |
| Price | $505 |
| Order / More Info | Human CD81 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Levy S, Todd SC and Maecker HT (1998). CD81 (TAPA-1): a molecule involved in signaltransduction and cell adhesion in the immune system. Annu Rev Immunol 16:89-109.Pileri P, Uematsu Y, Campagnoli S, Galli G, Falugi F, Petracca R, Weiner AJ, Houghton M,Rosa D, Grandi G and Abrignana S (1998). Binding of Hepatitis C Virus to CD81. Science282 no. 5390 pp. 938-941Flint M, von Hahn T, Zhang J, Farquhar M, Jones CT, Balfe P, Rice CM and McKeating JA(2006). Diverse CD81 Proteins Support Hepatitis C Virus Infection. Journal of Virology p.11331-11342Fofana I, Xiao F, Thumann C, Turek M, Zona L, Tawar RG, Grunert F, Thompson J, ZeiselMB, Baumert TF (2013). A Novel Monoclonal Anti-CD81 Antibody Produced by GeneticImmunization Efficiently Inhibits Hepatitis C Virus Cell-Cell Transmission. PLoS One21;8(5):e64221 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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