Edit |   |
Antigenic Specificity | IRF7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFNinducible gene expression in response to viral infection (1). IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3gamma/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-6, IRF-7, and IRF-8/ ICSBP. All IRF proteins share homology in their aminoterminal DNAbinding domains. IRF family members regulate transcription through interactions with proteins that share similar DNAbinding motifs, such as IFNstimulated response elements (ISRE), IFN consensus s |
Immunogen | Immunogen: A synthetic -peptide of human IRF7 |
Other Names | [IRF7; IRF7; IRF-7H; IRF7A; Interferon regulatory factor 7], [IRF7; IRF7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H; IRF-7] |
Gene, Accession # | Gene ID: 3665, NCBI: NP_001563.2, UniProt: Q92985 |
Catalog # | MBS125545 |
Price | $200, $275, $430 |
Order / More Info | IRF7 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Taniguchi, T. et al. (2001) Annu Rev Immunol 19, 623-55. 2. Honda, K. and Taniguchi, T. (2006) Nat Rev Immunol 6, 644-58. 3. Au, W.C. et al. (1998) J Biol Chem 273, 292-107. 4. Wathelet, M.G. et al. (1998) Mol Cell 1, 507-18. 5. Marie, I. et al. (1998) EMBO J 17, 6660-9. 6. Sato, M. et al. (2000) Immunity 13, 539-48. 7. Honda, K. et al. (2005) Nature 434, 772-7. 8. Colina, R. et al. (2008) Nature 452, 32-38. 9. Lin, R. et al. (2000) J Biol Chem 275, 34320-7. 10. Yang, H. et al. (2003) J Biol Chem 278, 15495-504. 11. Caillaud, A. et al. (2005) J Biol Chem 280, 17671-7. |