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Antigenic Specificity | PDHX |
Clone | [AT1E11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. |
Immunogen | Immunogen: Recombinant human PDHX (54-501aa) purified from E. coli. |
Other Names | [Pyruvate dehydrogenase protein X component mitochondrial; Pyruvate dehydrogenase protein X component; mitochondrial; DLDBP; E3BP; OPDX; PDX1; proX], [PDHX; PDHX; E3BP; OPDX; PDX1; proX; DLDBP; PDHXD; PDX1; E3BP] |
Gene, Accession # | [PDHX], Gene ID: 8050, NCBI: NP_003468, UniProt: O00330 |
Catalog # | MBS206610 |
Price | $240, $315 |
Order / More Info | PDHX Antibody from MYBIOSOURCE INC. |
Product Specific References | Aral B., et al. (1997) Am. J. Hum. Genet. 61: 1318-1326.; Hiromasa Y., et al. (2004) J. Biol. Chem. 279: 6921-6933. |