Edit |   |
---|---|
Antigenic Specificity | CTLA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
Immunogen | Immunogen: Recombinant protein of human CTLA4 Immunogen Species: Human |
Other Names | [ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12] |
Gene, Accession # | [CTLA4], Gene ID: 1493, NCBI: NP_001032720.1, UniProt: P16410 |
Catalog # | MBS9133975 |
Price | $200, $275, $430 |
Order / More Info | CTLA4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |