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Antigenic Specificity | Hif-1a |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | no preservative |
Size | 0.1 mg |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Hypoxia Inducible Factor 1 alpha (Hif-1a) is a transcription factor which accumulates in the nucleus of cells in most tissues which are subjected to hypoxic conditions. There it stabilizes by associating with Hif-1 beta (ARNT). Clone ANC10G3 binds to recombinant human Hif-1a in EIA, as well as native HIf1a present in nuclei of fixed permeabolized Nalm-6 cells cultured overnight with CoCl2 to simulate hypoxia. It interferes with binding of anti-Hif1a clone 546-16, suggesting that their epitopes overlap. |
Immunogen | Immunogen: Recombinant human Hif1a |
Other Names | [Human Hif-1a; Hypoxia Inducing Factor; Hif1a], [Hif-1a] |
Gene, Accession # | [Hif-1a], Gene ID: 3091, NCBI: NP_001521.1, UniProt: Q16665 |
Catalog # | MBS666934 |
Price | $310 |
Order / More Info | Hif-1a Antibody from MYBIOSOURCE INC. |
Product Specific References | 1) GL Wang, GL Song, et al. (1993) PNAS 90: 4304 |