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Antigenic Specificity | MUC1/CA15-3/EMA/CD227 (Epithelial Marker) |
Clone | [MUC1/2818R] |
Host Species | Rabbit |
Reactive Species | human, mouse. |
Isotype | IgG |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistology (Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb reacts with MUC1. The dominant epitope of this MAb has not yet been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and over expressed abundantly in > 90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four c-erbB receptors and localize with c-erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is |
Immunogen | Immunogen: Human milk-fat globule membranes (HMFGM) Positive Control: MCF-7 or MDA-231 Cells. Breast, Colon, Ovarian, Endometrial Carcinoma. |
Other Names | [Breast carcinoma-associated antigen DF3; CA15-3; H23AG; KL-6; MAM6; Mucin 1 cell surface associated;; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; Tumor-associated epithelial membrane antigen] |
Gene, Accession # | [MUC1], Gene ID: 4582, NCBI: NP_001018016.1, UniProt: P15941 |
Catalog # | MBS4380634 |
Price | $190, $340, $340 |
Order / More Info | MUC1/CA15-3/EMA/CD227 (Epithelial Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Stanley CM, Phillips TE. Am J Physiol. 1999; 277:G191-200. |