CHIA (N-term), 20-47 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CHIA (N-term), 20-47 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.27 |
| Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CHIA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-47 amino acids from the N-terminal region of human CHIA. CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins. |
| Immunogen | n/a |
| Other Names | [Acidic mammalian chitinase; AMCase; Lung-specific protein TSA1902; CHIA] |
| Gene, Accession # | [CHIA], Gene ID: 27159, NCBI: NP_001035713.1, UniProt: Q9BZP6 |
| Catalog # | MBS9207835 |
| Price | $165, $370 |
| Order / More Info | CHIA (N-term), 20-47 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Wu, A.C., et al. J. Allergy Clin. Immunol. 125(3):754-757(2010) Ober, C., et al. Curr Opin Allergy Clin Immunol 9(5):401-408(2009) Seibold, M.A., et al. J. Biol. Chem. 284(29):19650-19658(2009) Hartl, D., et al. J. Immunol. 182(8):5098-5106(2009) Lalaker, A., et al. Am J Rhinol Allergy 23(1):8-14(2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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