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Antigenic Specificity | Human ALK3 / BMPR1A |
Clone | [4B7B2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.05 mL |
Concentration | n/a |
Applications | IHC, IHC-Paraffin, Immunofluorescence, Western Blot, Flow Cytometry, ELISA. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human, Mouse. On ligand binding of BMP-2 and BMP-4, BMPR1A (a type I receptor) forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Targeted disruption of the BMPR1A receptor protein in the mesenchymal cells of the Mullerian ducts of mice leads to retention of oviducts and uteri in males. |
Immunogen | Immunogen Description: ALK3/BMPR1A antibody was raised against purified recombinant fragment of human BMPR1A (AA:179-378)expressed in E.Coli). Epitope: aa179-378 |
Other Names | [ALK3 / BMPR1A (aa179-378, clone 4B7B2) IHC-plus; BMPR1A; 10q23del; ALK3; ALK-3; BMP type-1A receptor; BMPR-1A; CD292; CD292 antigen; Activin receptor-like kinase 3; ACVRLK3; SKR5; Human ALK3; BMPR1A], [BMPR1A] |
Gene, Accession # | [ALK3], Gene ID: 657, NCBI: NP_004320.2, UniProt: P36894 |
Catalog # | MBS249195 |
Price | $530 |
Order / More Info | Human ALK3 / BMPR1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |