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Antigenic Specificity | PPM1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PPM1B protein. The protein encoded by PPM1B is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PPM1B protein at amino acid sequence of 310-390 |
Other Names | [Rabbit PPM1B; Protein phosphatase 2C isoform beta; PP2C-beta] |
Gene, Accession # | [PPM1B], Gene ID: 5495, NCBI: NP_808908, UniProt: O75688 |
Catalog # | MBS9710527 |
Price | $130, $220, $325 |
Order / More Info | PPM1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |