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Antigenic Specificity | CYP7A1 (C-term), 476-504 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rabbit) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CYP7A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human CYP7A1. CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. |
Immunogen | n/a |
Other Names | [Cholesterol 7-alpha-monooxygenase; CYPVII; Cholesterol 7-alpha-hydroxylase; Cytochrome P450 7A1; CYP7A1; CYP7] |
Gene, Accession # | [CYP7A1], Gene ID: 1581, NCBI: NP_000771.2, UniProt: P22680 |
Catalog # | MBS9200779 |
Price | $165, $370 |
Order / More Info | CYP7A1 (C-term), 476-504 Antibody from MYBIOSOURCE INC. |
Product Specific References | Lenicek,M., J. Lipid Res. 49 (12), 2664-2667 (2008) Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004) |