ZAP70 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityZAP70
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
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DescriptionThe Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement (1). Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck (2-6). Tyrosine phosphorylation correlates with increased Zap-70 kinase activity and downstream signaling events. Expression of Zap-70 is correlated with disease progression and survival in patients with chronic lymphocytic leukemia (7, 8).
ImmunogenImmunogen: Recombinant protein of human ZAP70 Observed Molecular Weight: 70kDa
Other Names[FLJ17670; FLJ17679; SRK; STD; TZK; ZAP-70]
Gene, Accession #[ZAP70], Gene ID: 7535, NCBI: AAH39039.1
Catalog #MBS2523010
Price$150, $225, $360
Order / More InfoZAP70 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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