PDE12 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PDE12 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 0.5 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Affinity Purified Phosphodiesterase 12 Antibody. Enzyme that cleaves 2', 5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3', 5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system. |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 370-420 on rat PDE12 protein. Immunoglobulin: IgG. Expression: Ubiquitous |
| Other Names | [2 PDE; 2' 5' phosphodiesterase 12; 2' phosphodiesterase; 2'-PDE; DKFZp667B1218; Pde12; Phosphodiesterase 12], [Pde12] |
| Gene, Accession # | [PDE12], NCBI: Q6TUH0, UniProt: Q6TUH0 |
| Catalog # | MBS543427 |
| Price | $390 |
| Order / More Info | PDE12 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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