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Antigenic Specificity | PKB alpha |
Clone | [IML-26] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, chicken |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Mouse IgG monoclonal antibody for PKB alpha, v-akt murine thymoma viral oncogene homolog 1 (AKT1) detection. Tested with WB in Human, mouse, rat, chicken. No cross reactivity with other proteins. Uniprot ID: P31749 Background: PKB alpha also knows as V-AKT murine thymoma vial oncogene homolog 1(ATK1). AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 461-477 of human PKB alpha/Akt1. |
Other Names | [RAC-alpha serine/threonine-protein kinase; v-akt murine thymoma viral oncogene homolog 1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; ONCOGENE AKT1; PROTEIN KINASE B-ALPHA; RAC SERINE/THREONINE PROTEIN KINASE; Protein kinase B; Proto-oncogene c-Akt; RAC-PK-alpha], [AKT1; AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; PKB; RAC; PKB; PKB alpha] |
Gene, Accession # | [AKT1], Gene ID: 207, NCBI: P31749.2, UniProt: P31749 |
Catalog # | MBS175042 |
Price | $280 |
Order / More Info | PKB alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |