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Antigenic Specificity | FGF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Fibroblast growth factors are a family of broad-spectrum growth factors influencing a plethora of cellular activities. The interaction of at least 23 ligands, 4 receptors and multiple coreceptors provides a dramatic complexity to a signaling system capable of effecting a multitude of responses (1, 2). Basic fibroblast growth factor (bFGF or FGF2), initially identified as a mitogen with prominent angiogenic properties, is now recognized as a multifunctional growth factor (3). It is clear that bFGF produces its biological effects in target cells by signaling through cell-surface FGF receptors. bFGF binds to all four FGF receptors. Ligand binding induces receptor dimerization and autophosphorylation, allowing binding and activation of cytoplas |
Immunogen | Immunogen: Recombinant protein of human FGF1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [FGF1; AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-alpha; FGFA; GLIO703; HBGF1] |
Gene, Accession # | [FGF1], Gene ID: 2246, NCBI: NP_000791.1, UniProt: P05230 |
Catalog # | MBS8504270 |
Price | $310 |
Order / More Info | FGF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Powers, C.J. et al. (2000) Endocrine-Related Cancer 7, 165-197. 2. Bansal, R. (2002) Dev. Neurosci. 24, 35-46. 3. Morrison, R.S. et al. (1994) J. Neurooncol. 18, 207-216. 4. Kouhara, H. et al. (1997) Cell 89, 693-702. 5. Mohammadi, M. et al. (1991) Mol. Cell. Biol. 11, 5068-5078. 6. Bikfalvi, A. (1995) Eur. J. Cancer 31A, 1101-1104. 7. Ledoux, D. et al. (1992) Prog. Growth Factor Res. 4, 107-120. |