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Antigenic Specificity | MMP12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.5 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MMP12 protein. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human matrix metallopeptidase 12 (macrophage elastase) |
Other Names | [ME; HME; MME; MMP-12] |
Gene, Accession # | [MMP12], Gene ID: 4321, NCBI: NP_002417.2, UniProt: P39900 |
Catalog # | MBS9414035 |
Price | $255 |
Order / More Info | MMP12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |