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Antigenic Specificity | Mouse CD83 |
Clone | [3D11] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Mouse CD83 antibody, clone 3D11 recognizes murine CD83, a 45kD type 1 glyoprotein belonging to the immunoglobulin superfamily. Originally described as a maturation marker for dendritic cells, CD83 plays a role in the regulation of antigen presentation, thymic T-cell maturation, B-cell function and peripheral T-cell activation. Activated dendritic cells and B-cells release a soluble form of CD83 that is reported to have an immunosuppressive effect, suggesting a therapeutic role for sCD83 in the regulation of immune disorders. |
Immunogen | Fusion Partners: Spleen cells from immunised rats were fused with cells of the P3X63.Ag8.653 mouse myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
Other Names | [CD83 antigen isoform 1; CD83 antigen; CD83 antigen; mCD83; CD83 antigen; CD_antigen: CD83], [Cd83; Cd83; mCD83] |
Gene, Accession # | [CD83], Gene ID: 12522, NCBI: NP_033986.1, UniProt: O88324 |
Catalog # | MBS217379 |
Price | $300 |
Order / More Info | Mouse CD83 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |