PIK3R1/2 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PIK3R1/2 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: Xenopus, bovine, mouse, rat) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PIK3R1/2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 337-370 amino acids from the Central region of human PIK3R1/2. Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. |
| Immunogen | n/a |
| Other Names | [Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha; PIK3R1; GRB1] |
| Gene, Accession # | [PIK3R1], Gene ID: 5295, NCBI: NP_001229395.1, UniProt: P27986 |
| Catalog # | MBS9206698 |
| Price | $165, $370 |
| Order / More Info | PIK3R1/2 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Skolnik E.Y.,et al.Cell 65:83-90(1991). Antonetti D.A.,et al.Mol. Cell. Biol. 16:2195-2203(1996). Udelhoven M.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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